Study Detail

TitleShugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere
Study TypeOther
Abstract To protect against aneuploidy, chromosomes must attach to microtubules from opposite poles (“biorientation”) prior to their segregation during mitosis. Biorientation relies on the correction of erroneous attachments by the aurora B kinase, which destabilizes kinetochore-microtubule attachments that .. [more]
Center NameGEO