Study Detail

Study TypeWhole Genome Sequencing
Abstract We plan on generating genomic data for historic Anopheles specimens in order to investigate the past century of evolutionary responses to vector control measures. Our DNA of interest is fragmented and contains base modifications, which we need to control for during library preparation and sequencing .. [more]
Description Vector control measures, such as insecticides, have been game changers in reducing the burden of malaria throughout sub-Saharan Africa ever since widespread use begun in the 1950s. However, it is known from present-day genomic studies that insecticide resistance in Anopheles mosquitoes is on the ris .. [more]
Center NameWellcome Sanger Institute