Study Detail

TitleElevated coding mutation rate during the reprogramming of human somatic cells into induced pluripotent stem cells
Study TypeExome Sequencing
Abstract Mutations in human induced pluripotent stem cells (iPSCs) pose a risk for their clinical use due to preferential reprogramming of mutated founder cell and selection of mutations during maintenance of iPSCs in cell culture. It is unknown, however, if mutations in iPSCs are due to stress associated wi .. [more]
Center NameOICR