Study Detail

TitlePopulation changes of heteroresistant Mycobacterium tuberculosis harbouring rare resistance-conferring mutations in gyrA and rpoB implies an epistatic interaction of the mutations related to strain fitness in pre-XDR-TB patient
Study TypeOther
Abstract The goals of this study is to unveil the genomic factors underlying the uniqueness of this clinical case which is highlighted as follows: 1) the acquisitions of RIF-resistant genotypes (rpoB V170F) occurred under a multi-drug therapy after exclusion of RIF, 2) the sub-clone which harbors rare resist .. [more]
Description The goals of this study is to unveil the genomic factors underlying the uniqueness of this clinical case which is highlighted as follows: 1) the acquisitions of RIF-resistant genotypes (rpoB V170F) occurred under a multi-drug therapy after exclusion of RIF, 2) the sub-clone which harbors rare resist .. [more]
Center NameKIH