Study Detail

TitleHsp90 facilitates accurate loading of precursor piRNAs into PIWI proteins
Study TypeTranscriptome Analysis
Abstract PIWI-interacting RNAs (piRNAs) defend the genome against transposon activity in animal gonads. The Hsp90 chaperone machinery has been implicated in the piRNA pathway, but its exact role remains obscure. Here, we examined the effect of 17-N-allylamino-17-demethoxygeldanamycin (17-AAG), an Hsp90-speci .. [more]
Center NameUT-GALS