Title | Transcriptome-wide analysis of imprinted gene expression in cloned mice |
Study Type | Transcriptome Sequencing |
Abstract | Somatic cell nuclear transfer (SCNT) can produce viable individuals, but the success rate is very low. While many works hypothesized that defects in SCNT-derived animals are caused by abnormal imprinted gene expression, few non-random loss of imprinting have been found. In this study, we performed a .. [more] transcriptome-wide analysis of imprinted gene expression in cloned mouse placenta and brain, and found that many imprinted genes showed abnormal expression in cloned mice. [less] |
Description | |
Center Name | TOHOKU |