Study Detail

TitleSurvey of short RNA expression after interference of RNAs expressed from retrotransposons
Study TypeTranscriptome Analysis
Abstract Short RNAs (sRNAs) originating in pseudogenes and retrotransposons have been demonstrated to function as trans-regulatory elements in mammals. It followed therefore that the observed myogenesis phenotypes may have been caused by the perturbation of LINE-1 derived .. [more]
Description Here, we report in detail the first use of RNA interference against LINE-1 transposed element RNAs, in an effort to ascertain their functional significance. Using mouse myoblasts as a model system, we observed clear phenotypic consequences post knock-down of LINE- .. [more]
Center NameRIKEN_OSC